Fenobibrate Tablets: Uses, Dosage, and Safety

When working with Fenobibrate Tablets, oral tablets containing fenobibrate, a lipid‑lowering drug. Also known as fenofibrate tablets, it helps lower triglycerides and raise HDL cholesterol, you’re dealing with a medication that belongs to the fibrate class. The active ingredient, Fenobibrate, the compound that activates lipid‑metabolizing pathways, works by turning on PPAR‑alpha, a nuclear receptor that controls fatty‑acid oxidation. This triple‑action—lowering triglycerides, raising HDL, and modestly reducing LDL—makes fenobibrate tablets a go‑to option for people struggling with Hypertriglyceridemia, high blood triglyceride levels. In short, fenobibrate tablets encapsulate a targeted approach to lipid management.

Why does the body need a fibrate when Statins, drugs that primarily lower LDL cholesterol are so common? Statins excel at dropping “bad” cholesterol, but they often leave triglycerides high. Fenobibrate tablets fill that gap by specifically targeting triglyceride‑rich particles called VLDL. The drug reduces VLDL production in the liver and speeds up its clearance from the bloodstream. If you’ve been told your triglycerides are over 200 mg/dL, a fibrate can bring them down into a safer range, lowering the risk of pancreatitis and cardiovascular events. Think of statins and fenobibrate tablets as teammates: one tackles LDL, the other tames triglycerides, together delivering a more balanced lipid profile.

Dosage matters. Most adults start with a 145 mg tablet taken once daily with food to boost absorption. Some clinicians split the dose—half in the morning, half at night—to smooth out any stomach upset. If you have kidney impairment, the dose may be reduced to 48 mg or taken every other day, because fenobibrate tablets are cleared partly through the kidneys. Brand‑name and generic versions contain the same active ingredient, so cost is usually the deciding factor. Consistency is key: skipping doses can cause triglyceride spikes, while taking the tablet at the same time each day keeps blood levels steady. Always follow your prescriber’s instructions and report any unusual muscle pain or liver‑function changes.

Interactions are a real concern. Fenobibrate tablets can boost the effect of anticoagulants like warfarin, raising bleeding risk. They also interfere with some cholesterol‑lowering drugs, especially high‑dose statins, increasing the chance of muscle damage (myopathy). If you’re on a bile‑acid sequestrant, take fenobibrate tablets at least two hours apart to avoid reduced absorption. Alcohol, high‑fat meals, and grapefruit juice can all tip the balance, sometimes causing liver enzyme elevations. People with liver disease should avoid fenobitrate tablets altogether, as the liver processes most of the drug. Always keep a current medication list handy and discuss any supplements—especially omega‑3 fatty acids or niacin—with your healthcare provider.

What’s Next?

Now that you know what fenobibrate tablets are, how they work, the typical dosing schedule, and the key safety points, you’re ready to dive deeper. Below you’ll find a curated collection of articles covering everything from detailed side‑effect profiles to real‑world patient experiences, drug‑interaction guides, and tips for managing high triglycerides without sacrificing quality of life. Explore the posts to get actionable advice and up‑to‑date information that can help you make the most of your treatment plan.