Prelone (prednisolone) is widely used for tackling acute asthma and inflammatory conditions, but there are several alternatives worth considering. This article investigates six alternatives, including dexamethasone and methotrexate, comparing their features, benefits, and potential drawbacks. Readers will gain insight into effective steroid-sparing options, helping them make informed decisions about their treatment choices. By looking into immunosuppressive drugs like azathioprine, one can find viable ways to manage autoimmune diseases and reduce steroid dependency.