Stromectol alternatives: what works instead of ivermectin

Looking for alternatives to Stromectol (ivermectin)? Whether you can’t take ivermectin, you want a topical option, or your infection needs a different approach, there are clear alternatives. Below I’ll walk you through common substitutes, when they matter, and how to pick one with your doctor.

Common medical alternatives

For scabies:

  • Permethrin 5% cream — a topical prescription that’s often the first choice for classic scabies. You apply it overnight to the whole body; it kills mites on contact.

  • Benzyl benzoate — another topical option used in some countries. It can irritate sensitive skin but is an effective alternative where permethrin isn’t available.

  • Crotamiton or sulfur ointments — older options that still work for some people, especially if other meds cause side effects.

For intestinal worms (like strongyloidiasis, threadworms, some nematodes):

  • Albendazole and mebendazole — oral anti-worm drugs commonly used worldwide. They work well for many types of roundworms and are often prescribed when ivermectin isn’t suitable.

  • Thiabendazole — used in some cases, though it can have more side effects than albendazole.

For onchocerciasis (river blindness) or infections that involve Wolbachia bacteria:

  • Doxycycline — not a direct parasite killer, but it targets Wolbachia (symbiotic bacteria inside some parasites). A multi-week course can reduce parasite survival and is used in specific settings.

How to pick the right option

Ask these questions when you talk with your clinician: What parasite is confirmed by tests? Are you pregnant or breastfeeding? Do you have liver disease or other meds that might interact? The right choice depends on diagnosis, severity, age, and safety for pregnancy.

Remember side effects differ. Topical treatments like permethrin usually cause less systemic effects than oral drugs. Albendazole and mebendazole are generally well tolerated, but your doctor may order blood tests for longer courses. Doxycycline requires weeks of treatment and isn’t for children under eight or pregnant people.

One last practical point: ivermectin became a controversial topic during the COVID-19 pandemic. Don’t use it or any alternative for conditions not supported by clear medical advice. Follow test results and trusted treatment guidelines, and avoid self-medicating with drugs meant for other uses.

If you suspect a parasitic infection, get tested and consult a healthcare provider. They’ll pick the safest, most effective alternative to Stromectol for your situation and explain how to use it properly.

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